PharmaPHILIA - Extracting Concepts Of Medical With Rph FIA

Neurotransmitter: C hemical signals involved in communication b/w nerve cells, and b/w  nerve cells & effector cells e.g Norepinephrine, Epinephrine, Acetylcholine, Dopamine,  Serotonin, Histamine, GABA  Hormone : Released from endocrine cells, into blood stream, travel throughout the body  Local mediators: cells secrete the chemicals act locally in their immediate environment  e.g Histamine, Prostaglandins  Second Messenger: produced in response to neurotransmitter binding to receptors, translate the extracellular signal into response e.g cAMP, IP3, DAG Botulinum  Toxin:  blocked release of Ach from vesicles into Synaptic cleft Spider Venom causes release of Ach from vesicles  AcetylCholineEsterases: degrade Ach in the synaptic cleft by hydrolyzing  Ca2+ :  Elevated level of calcium causes fusion of vesicles & release of Ach in synaptic  cleft  Muscarinic Receptors:   G-protein coupled receptors---Bind with...

Nervous system divided in 1)CNS 2)PNS Peripheral Nervous sys .  PNS: 1)Efferant division (brain to peripheral) 2)Afferant division(peripheral to brain)  Efferant Division: Motor neurons  1)ANS Autonomic Nervous Sys. 2)Somatic sys.  ANS divided in  1)ENS (Enteric nervous sys)  2)PNS ( parasympathic nervous sys)  3)SNS  (sympathic nervous sys). ANS : Involuntary/Visceral/Vegetative=regulates the everyday requirement of vital bodily  function without conscious participation of mind  Somatic SYS .: Voluntary control of functions such as contraction of skeletal muscle   Sympathic Neurons: 👉Preganglionic neurons of sympathetic come from T1-L2 of spinal  cord-------short compare to postganglionic neurons  Response to stressful situation such as trauma,cold,hypoglycemia,exercise  Fight or Flight response ---release of adrenaline(epinephrine) & lesser amount of  norepinephrinee. Parasympathetic system: maintain the...