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PHARMACEUTICS TEST PAPER FOR GAT PREPARATION AND PHARMACEUTICAL INTERVIEW

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  Directions for questions 1-28: Each of the questions, statements, or incomplete statements in this section can be correctly answered or completed by one of the suggested answers or phrases. Choose the best answer. 1. Which substance is classified as a weak electrolyte? (A) glucose (B) urea (C) ephedrine (D) sodium chloride (E) sucrose 2. The pH value is calculated mathematically as the (A) log of the hydroxyl ion (OH-) concentration. (B) negative log of the OH-  concentration. (C) log of the hydrogen ion (H+) concentration. (D) negative log of the H+ concentration. (E) ratio of H+/OH- concentration. 3. Which property is classified as colligative? (A) solubility of a solute (B) osmotic pressure (C) hydrogen ion (H+) concentration (D) dissociation of a solute (E) miscibility of the liquids 4. The colligative properties of a solution are related to the (A) pH of the solution. (B) number of ions in the solution. (C) total number of solute particles in the soluti...

COLLIGATIVE PROPERTIES - PHARMACEUTICAL PRINCIPLES AND DRUG DOSAGE FORMS

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  Colligative properties of solutions are properties that depend upon the concentration of solute molecules or ions, but not upon the identity of the solute. Colligative properties include vapor pressure lowering, boiling point elevation, freezing point depression, and osmotic pressure. Lowering the Vapor Pressure: Let's first remind ourselves about what vapor pressure is and what affects it chemically and physically. In a closed container, a liquid will evaporate until an equal amount of molecules are returning to the liquid state as there are escaping into the gas phase. The pressure of the vapor phase above the liquid at this point is called the equilibrium vapor pressure. This vapor pressure is dependent on a number of factors, including the temperature of the system (kinetic energy is required to help the molecules escape into the gas phase), the pressure of the system (high pressure can keep the gas contained in the liquid e.g. a bottle of coke), and also the intermolecular f...